Author

P. J. Fleming

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 4 Ecology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:cell signaling & trafficking· 2 Organism:bacteria (other)· 1 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Research Focus:ecology & biodiversity· 1 Research Focus:host-pathogen & immune response· 1 Assay:imaging· 1

Frequent Co-Authors

K. G. Fleming· 4 shared T. Devlin· 2 shared A. Glen· 1 shared A. M. Faustino· 1 shared A. M. Plummer· 1 shared A. Mather-Zardain· 1 shared A. Y. B. Vazquez· 1 shared B. E. West· 1 shared

Activity by Year

2019-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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4 shared papersBiophysics

K. G. Fleming

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Pharmaceutical agent cetylpyridinium chloride inhibits immune mast cell function by interfering with calcium mobilization

B. Obeng, C. M. Potts, B. E. West, J. E. Burnell, P. J. Fleming, J. K. Shim, M. S. Kinney, E. L. Ledue, S. Sangroula, A. Y. B. Vazquez, J. A. Gosse

This study shows that cetylpyridinium chloride inhibits mast cell degranulation by disrupting calcium mobilization without affecting plasma membrane potential or pH.

Food and Chemical Toxicology · Sep 1, 2023Peer-reviewedPharmacology & Toxicology

Generation of Unfolded Outer Membrane Protein Ensembles Targeted by Hydrodynamic Properties

T. Devlin, P. J. Fleming, N. Loza, K. G. Fleming

The paper models unfolded outer membrane protein ensembles using experimental data and simulations to understand their conformational differences.

bioRxiv · Oct 31, 2022 · PreprintBiophysics

Revisiting Macromolecular Hydration with HullRadSAS

P. J. Fleming, J. J. Correia, K. G. Fleming

The paper introduces a method to calculate two types of macromolecular hydration, surface shell water and entrained water, to better explain hydration-related properties and hydrodynamic behavior.

bioRxiv · Oct 20, 2022Biophysics

SurA is a "Groove-y" Chaperone That Expands Unfolded Outer Membrane Proteins

D. C. Marx, A. M. Plummer, A. M. Faustino, M. A. Roskopf, M. J. Leblanc, T. Devlin, H. J. Lessen, B. T. Amann, P. J. Fleming, S. Krueger, S. D. Fried, K. G. Fleming

This paper investigates how SurA, a bacterial chaperone, interacts with unfolded outer membrane proteins (uOMPs) using structural biology techniques, revealing distinct binding modes and a mechanism for uOMP expansion.

bioRxiv · Dec 17, 2019Biophysics

ClassifyMe: a field-scouting software for the identification of wildlife in camera trap images.

G. Falzon, C. Lawson, K.-W. Cheung, K. Vernes, G. Ballard, P. J. Fleming, A. Glen, H. Milne, A. Mather-Zardain, P. D. Meek

ClassifyMe is a software tool for automated wildlife identification in camera trap images, enabling field and office use with local processing and minimal cost.

bioRxiv · May 24, 2019Ecology

Protein structure prediction and design in a biologically-realistic implicit membrane

R. F. Alford, P. J. Fleming, K. G. Fleming, J. J. Gray

This paper develops an implicit membrane model for protein structure prediction and design, improving accuracy in membrane protein properties and sequence recovery.

bioRxiv · May 8, 2019Biophysics