A Precisely Controlled Long-Acting Immunosuppression Platform Enables Prolonged Survival of Vascularized Composite Allografts
Sohyung Lee, Fatih Zor, Yalçın Külahçı, John Joseph, Hüseyın Karagöz, Shumaim Barooj, Gunjan Malik, Dongsung Park, James N. Luo, Lingyun Zhu, Ally Wang, Krisco Chung, Nancy Li, Purna Shah, Eli Agus, , Vijay S. Gorantla
PRECISE, a long-acting immunosuppression platform, maintains therapeutic drug levels and prolongs graft survival in VCA models through precise control of tacrolimus and rapamycin release.
bioRxiv · Nov 7, 2025 · PreprintBioengineering