HIV-1 infection induces Vif-mediated SUMOylation of host RNA splicing factors important for proper viral RNA splicing
Demetra P. Kelenis, Jeffrey R. Johnson, Simone Sidoli, Ann Emery, Ronald Swanstrom, Luke J Hawkins, Kaila Mckie, Tegh Pawar, Stephen P. Goff
This study identifies HIV-1-induced SUMOylation of host RNA splicing factors, mediated by Vif, which regulates viral RNA splicing and infectivity.
Proceedings of the National Academy of Sciences · Apr 28, 2026Peer-reviewedMolecular Biology