Ronald I. Swanstrom

HIV-1 infection induces Vif-mediated SUMOylation of host RNA splicing factors important for proper viral RNA splicing

This study identifies HIV-1-induced SUMOylation of host RNA splicing factors, mediated by Vif, which regulates viral RNA splicing and infectivity.

Cotranslational folding and maturation of HIV-1 protease

The paper studies cotranslational folding and autoproteolytic processing of HIV-1 protease during viral particle assembly.

The role of Nef in the long-term persistence of the replication-competent HIV reservoir in South African women

This study investigates how HIV-1 Nef's ability to downregulate MHC-I affects the size of the replication-competent viral reservoir in South African women on ART, finding a significant association between MHC-I downregulation and reservoir size.

HIV-1 single transcription start site mutants display complementary replication functions that are restored by reversion

This study examines HIV-1 mutants that produce only one transcription start site RNA and finds that they display complementary replication functions restored by reversion.

HIV-1 Rebound Virus Consists of a Small Number of Lineages That Entered the Reservoir Close to ART Initiation

The paper identifies that HIV-1 rebound virus primarily originates from a small number of lineages that entered the reservoir near ART initiation, despite the reservoir containing older sequences.

Changes in Cerebrospinal Fluid Proteins across the Spectrum of Untreated and Treated Chronic HIV-1 Infection

The paper measures CSF proteins in HIV-1 infected and uninfected individuals, identifying patterns of protein changes associated with CNS injury and treatment effects.

Epitranscriptomic addition of m6A regulates HIV-1 RNA stability and alternative splicing

This paper shows that m6A methylation regulates HIV-1 RNA stability and alternative splicing through YTHDC1 and YTHDF2.