Intersecting impact of CAG repeat and Huntingtin knockout in stem cell-derived cortical neurons
Jennifer T. Stocksdale, Matthew Joseph Leventhal, Stephanie Lam, Yuxin Xu, Yi Wang, Keona Q. Wang, Reuben Thomas, Zohreh Faghihmonzavi, Yogindra Raghav, Charlene Smith-Geater, Jie Wu, Ricardo Miramontes, Kanchan Sarda, Heather Johnston, Min‐Gyoung Shin, , Leslie Michels Thompson
This study compares the effects of HTT knockout and CAG repeat expansion in cortical neurons, identifying shared and distinct biological pathways involved in HD.
Neurobiology of Disease · Apr 19, 2025Peer-reviewedCell Biology