Author

Yuxin Xu

Harvard UniversityORCID 0000-0002-0200-4633Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Yuxin Xu2 papers · Jilin University

Biology Disciplines

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Cell Biology· 2 Genetics· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:mouse· 1

Frequent Co-Authors

Amy DeikiD· 2 shared Clary B. ClishiD· 2 shared Kevin H. BullockiD· 2 shared Taiji MizoguchiiD· 2 shared Taylor Hanta NagaiiD· 2 shared Charlene Smith-GeateriD· 1 shared Chris Paiz· 1 shared Dan P. FelsenfeldiD· 1 shared

Activity by Year

2019-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersCell Biology

Amy DeikORCID

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Author profile →

3 papers

Recent·Most cited

Intersecting impact of CAG repeat and Huntingtin knockout in stem cell-derived cortical neurons

Jennifer T. Stocksdale, Matthew Joseph Leventhal, Stephanie Lam, Yuxin Xu, Yi Wang, Keona Q. Wang, Reuben Thomas, Zohreh Faghihmonzavi, Yogindra Raghav, Charlene Smith-Geater, Jie Wu, Ricardo Miramontes, Kanchan Sarda, Heather Johnston, Min‐Gyoung Shin, , Leslie Michels Thompson

This study compares the effects of HTT knockout and CAG repeat expansion in cortical neurons, identifying shared and distinct biological pathways involved in HD.

Neurobiology of Disease · Apr 19, 2025Peer-reviewedCell Biology

ANGPTL3 regulates the peroxisomal translocation of SmarcAL1 in response to cell growth states

Taylor Hanta Nagai, Taiji Mizoguchi, Yanyan Wang, Amy Deik, Kevin H. Bullock, Clary B. Clish, Yuxin Xu

This study shows that ANGPTL3 regulates SmarcAL1 translocation to peroxisomes, affecting lipid metabolism and TG storage in response to cell growth states.

Scientific Reports · Feb 11, 2025Peer-reviewedCell Biology

EDEM3 modulates plasma triglyceride level through its regulation of LRP1 expression

Yuxin Xu, Gina Marie Peloso, Taylor Hanta Nagai, Taiji Mizoguchi, Amy Deik, Kevin H. Bullock, Honghuang Lin, Kiran Musunuru, Qiong Yang, Ramachandran Srini Vasan, Robert Edgardo Gerszten, Clary B. Clish, Daniel James Rader, Sekar Kathiresan

The paper identifies a missense variant in EDEM3 associated with lower blood triglyceride levels and shows EDEM3 deficiency increases LRP1 expression, reducing plasma TG through enhanced lipoprotein uptake.

iScience · Jan 1, 2019Peer-reviewedGenetics