Author

Kangni Zou

Hospital for Sick Children

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Biology Disciplines

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Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

Greg L. BeilhartziD· 1 shared Huazhu LiangiD· 1 shared Roman A. MelnykiD· 1 shared Shi Bo CaoiD· 1 shared Xindi Wang· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

5 top collaborators · 10 mutual co-author links

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1 shared paperPharmacology & Toxicology

Greg L. BeilhartzORCID

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1 paper

Recent·Most cited

Balancing receptor engagement and payload catalytic activity broadens the therapeutic window of immunotoxins

Huazhu Liang, Greg L. Beilhartz, Xindi Wang, Kangni Zou, Shi Bo Cao, Roman A. Melnyk

This study shows that reducing the catalytic activity of immunotoxins while balancing receptor engagement improves their selectivity and therapeutic window.

bioRxiv · Oct 2, 2026 · PreprintPharmacology & Toxicology