Experimental glaucoma retinal proteomics identifies mutually exclusive and overlapping molecular characteristics with human glaucoma
Mehdi Mirzaei, Vivek Gupta, Nitin Chitranshi, Liting Deng, Kanishka Pushpitha, Mojdeh Abbasi, Joel M. Chick, Rashi Rajput, Yunqi Wu, Matthew J. McKay, Ghasem Hosseini Salekdeh, Veer Bala Gupta, Paul A. Haynes, Stuart L. Graham
This study compares proteomic changes in a rat glaucoma model with human glaucoma, identifying shared and distinct molecular features related to oxidative stress, mitochondrial dysfunction, and immune pathways.
bioRxiv · May 14, 2020 · PreprintNeuroscience