Epigenetic derepression of H3K9me3 mitigates Alzheimer-related pathology and improves cognition via immunomodulation and Vgf induction
Dieu-Trang S. Fuchs, Jean‐Philippe Vit, Altan Rentsendorj…·Maya Koronyo‐Hamaoui
This study shows that inhibiting H3K9me3 with ETP69 reduces AD pathology and improves cognition by modulating neuroinflammation and inducing Vgf.