Author

Kar Lye Tam

University of Malaya

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Evolutionary Biology· 2 Physiology· 1 Scientific Communication & Education· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Approach:statistical model· 3 Assay:clinical cohort / trial· 2 Research Focus:development & morphogenesis· 2 Research Focus:host-pathogen & immune response· 2 Research Focus:metabolism & bioenergetics· 2 Research Focus:benchmarking· 1 Approach:experimental assay· 1

Frequent Co-Authors

Amanda J. LeaiD· 4 shared Ian J. WallaceiD· 4 shared Tan Bee Ting A P Tan Boon Huat· 4 shared Thomas S. KraftiD· 4 shared Vivek Vasi VenkataramaniD· 4 shared Colin Nicholas· 3 shared Izandis bin Mohd SayediD· 3 shared Yvonne Ai Lian LimiD· 3 shared

Activity by Year

2026-2026 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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4 shared papersEvolutionary Biology

Amanda J. LeaORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Divergent Biological Consequences of APOE Isoforms Across Industrialized and Non-Industrial Environments

Marina M. Watowich, Rachel M. Petersen, Layla Brassington, Audrey M. Arner, Grace Rodenberg, Tan Bee Ting A P Tan Boon Huat, Kar Lye Tam, Em Schellenberg, Izandis bin Mohd Sayed, Echwa John, John C. Kahumbu, Benjamin Muhoya, Michael Gurven, Benjamin C. Trumble, Sospeter Ngoci Njeru, , Amanda J. Lea

This study examines how APOE isoforms affect biological outcomes in industrialized and non-industrial environments, finding lifestyle-dependent effects and weak reproductive benefits for APOE ε4.

PLoS Genetics · Sep 8, 2026Peer-reviewedEvolutionary Biology

Recent lifestyle change impacts sleep and circadian rhythms among the Indigenous peoples of Peninsular Malaysia

Kathleen D. Reinhardt, Thomas S. Kraft, Amanda J. Lea, Ian J. Wallace, Yvonne Ai Lian Lim, Colin Nicholas, Tan Bee Ting A P Tan Boon Huat, Kar Lye Tam, Steven K. W. Chow, Izandis bin Mohd Sayed, Kamal Solhaimi Fadzil, Michael C. Antle, Vivek Vasi Venkataraman

This study examines how lifestyle changes in Indigenous Orang Asli communities in Malaysia affect sleep patterns and circadian rhythms, finding delayed timing and shorter duration with improved quality.

Proceedings of the Royal Society B Biological Sciences · Aug 5, 2026Peer-reviewedPhysiology

Development and assessment of tailored illustrations to enhance community understandings of genetics topics

Audrey M. Arner, Tobias C. McCabe, Amanda Seyler, Siti Nurani Zamri, Tan Bee Ting A P Tan Boon Huat, Kar Lye Tam, Patriciah Kinyua, Echwa John, Sospeter Ngoci Njeru, Yvonne AL Lim, Michael Gurven, Colin Nicholas, Julien F. Ayroles, Vivek Vasi Venkataraman, Thomas S. Kraft, , Amanda J. Lea

The paper develops and evaluates tailored illustrations to improve community understanding of genetics concepts through iterative feedback and analysis of engagement patterns.

American Journal of Biological Anthropology · Jul 1, 2026Peer-reviewedScientific Communication & Education

Early life environments shape adult cardiometabolic health during rapid lifestyle change

Rachel M. Petersen, Robert L. Tennyson, Tan Bee Ting A P Tan Boon Huat, Kar Lye Tam, Marina M. Watowich, Izandis bin Mohd Sayed, Colin Nicholas, Kamal Solhaimi Fadzil, Kee Seong Ng, Yvonne Ai Lian Lim, Vivek Vasi Venkataraman, Ian J. Wallace, Thomas S. Kraft, Amanda J. Lea

The paper examines how early life environments affect adult cardiometabolic health in the Orang Asli, finding support for developmental constraints over predictive adaptive responses.

Proceedings of the Royal Society B Biological Sciences · Apr 22, 2026Peer-reviewedEvolutionary Biology