High-resolution single-cell sequencing of malaria parasites
Simon G. Trevino, Standwell C. Nkhoma, Shalini Nair, Benjamin J. Daniel, Karla Moncada, Stanley Khoswe, Rachel L. Banda, François Henry Nosten, Ian H. Cheeseman
This paper develops a single-cell genomics protocol to reconstruct haplotypes of Plasmodium falciparum parasites and analyzes 48 cells from a malaria infection to estimate clonality and haplotype relatedness.
Genome Biology and Evolution · Dec 1, 2017Peer-reviewedGenomics