Resolving within-host malaria parasite diversity using single-cell sequencing
Standwell C. Nkhoma, Simon G. Trevino, Karla M. Gorena…·Ian H. Cheeseman
This study uses single-cell sequencing to analyze within-host diversity of Plasmodium falciparum in malaria patients, revealing up to seventeen unique lineages per patient and suggesting co-transmission from a single mosquito is more common than superinfection.