The sensitising effect of IgG in fibromyalgia syndrome is mediated by Mrgprb2 in mast cells
Karla R. Sanchez, Jamie Burgess, Qin Zheng, Uazman Alam, Harvey Neiland, Richard Berwick, David A. Andersson, Samantha K. Korver, Anne Worthington, Andreas Göebel, Xinzhong Dong
This study shows that IgG in fibromyalgia syndrome activates mast cells via Mrgprb2, leading to hypersensitivity and inflammation.
bioRxiv · May 15, 2025 · PreprintImmunology