Facilitation of Cav3.2 channel gating in pain pathways reveals a novel mechanism of serum-induced hyperalgesia
Karolina Sanner, Sarah Kawell, J. Grayson Evans, Vida Elekovic, MacKenzie Walz, Sonja Lj. Joksimovic, Srdjan M. Joksimovic, Rebecca Donald, Maja A. Tomic´, Peihan Orestes, Simon Feseha, Annemarie Dedek, Seyed Mohammadreza Ghodsi, Isabella P. Fallon, Jeong Han Lee, , Slobodan M. Todorovic
The paper identifies a novel mechanism of serum-induced hyperalgesia through the facilitation of Cav3.2 channel gating by the peptide albumin (1-26).
bioRxiv · Jan 3, 2025 · PreprintNeuroscience