Potential nematicides identified through targeted in vivo screening of a 5-HT-gated chloride channel, MOD-1
Fernando Calahorro, Yogendra K. Gaihre, Katarzyna Marek, Claude Charvet, Cédric Neveu, Mirela C Coke, Catherine J. Lilley, Peter Urwin, Lindy M. Holden-Dye, Vincent M. O'Connor
The paper identifies potential nematicides targeting MOD-1, a 5-HT-gated chloride channel in nematodes, using a screening platform and validates their efficacy against plant parasitic nematodes.
bioRxiv · Jan 27, 2026 · PreprintPharmacology & Toxicology