Fernando Calahorro

BARMIE predicts chemical binding affinities to steroid receptors across species to identify environmentally relevant chemicals and vulnerable species.

The paper identifies potential nematicides targeting MOD-1, a 5-HT-gated chloride channel in nematodes, using a screening platform and validates their efficacy against plant parasitic nematodes.

The paper demonstrates that using co-CRISPR marker genes in C. elegans can lead to hidden genomic rearrangements that affect gene function, emphasizing the need for sequencing co-CRISPR genes after CRISPR editing.

This study investigates the role of neuroligin in social behavior in C. elegans by using CRISPR/Cas9 to edit an autism-associated mutation and shows its impact on social circuitry.

This study shows that C. elegans nlg-1 mutants are defective in food-induced pharyngeal pumping, despite normal chemotaxis, suggesting neuroligin regulates feeding circuits outside the pharynx.