An Automated Scientist to Design and Optimize Microbial Strains for the Industrial Production of Small Molecules
Amoolya H. Singh, Benjamin Kaufmann-Malaga, Joshua A. Lerman, Daniel P. Dougherty, Yang Zhang, Alexander L. Kilbo, Erin H. Wilson, Chiam Yu Ng, Onur Erbilgin, Kate A. Curran, Christopher D. Reeves, John E. Hung, Simone Mantovani, Zachary A. King, Marites J. Ayson, , Adam L. Meadows
The paper introduces an automated system called Lila to design and optimize microbial strains for producing small molecules, achieving high titers for naringenin and creating strains for 242 molecules.
bioRxiv · Jan 3, 2023 · PreprintSynthetic Biology