Author

Kate J. Lewis

Massachusetts Eye and Ear Infirmary

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Genetics· 1

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Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Assay:electronic health records· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:mouse· 1

Frequent Co-Authors

Anil K. ChekuriiD· 1 shared Caitlin Elizabeth Keiper· 1 shared Dadi GaoiD· 1 shared Elisabetta MoriniiD· 1 shared Frances B. LefcortiD· 1 shared Hui‐Chen ChengiD· 1 shared Luk H. VandenbergheiD· 1 shared Matthew Chagnon· 1 shared

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2026-2026 · peak 1/yr

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1 shared paperGenetics

Anil K. ChekuriORCID

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1 paper

Recent·Most cited

ELP1 Gene Augmentation Restores Visual Function in a Mouse Model of Familial Dysautonomia

Hui‐Chen Cheng, Swanand Koli, Kate J. Lewis, Sara Ketchale, Yasaman Anvarinia, Morgan P. Erdoes, Yating Liu, Caitlin Elizabeth Keiper, Reynette Estelien, Matthew Chagnon, Luk H. Vandenberghe, Dadi Gao, Frances B. Lefcort, Elisabetta Morini, Susan A. Slaugenhaupt, Anil K. Chekuri

This study shows that gene supplementation with ELP1 in a mouse model of familial dysautonomia rescues retinal structure and function, suggesting it as a potential therapy for FD-associated optic neuropathy.

Molecular Therapy · Apr 25, 2026Peer-reviewedGenetics