Optimized chemogenetic ablation and regeneration of enteric nervous system neurons in zebrafish
Mujahid Shah, Katherine K. Moran, Helen E. Rueckert, Abigail V. Sharrock, David F. Ackerley, Jeff S. Mumm, Julia Ganz
This study develops a chemogenetic ablation model in zebrafish to study ENS neuron regeneration, showing complete restoration of most neuron subtypes but partial recovery of serotonergic neurons.
Stem Cell Reports · Jul 1, 2026Peer-reviewedNeuroscience