Author

Katherine R. Singleton

Duke University

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Systems Biology· 1

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Approach:experimental assay· 1

Frequent Co-Authors

Annamarie E. AlleniD· 1 shared Jason W. LocasaleiD· 1 shared Jun O. LiuiD· 1 shared Kris C. WoodiD· 1 shared Maria V. LibertiiD· 1 shared Vijyendra RameshiD· 1 shared Ziwei DaiiD· 1 shared Zufeng GuoiD· 1 shared

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2019-2019 · peak 1/yr

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1 shared paperSystems Biology

Annamarie E. AllenORCID

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1 paper

Recent·Most cited

Evolved resistance to GAPDH inhibition results in loss of the Warburg Effect but retains a different state of glycolysis

Maria V. Liberti, Annamarie E. Allen, Vijyendra Ramesh, Ziwei Dai, Katherine R. Singleton, Zufeng Guo, Jun O. Liu, Kris C. Wood, Jason W. Locasale

This study evolves resistance to GAPDH inhibition and shows that cells lose the Warburg Effect but maintain a distinct glycolytic state with different metabolic dependencies.

Journal of Biological Chemistry · Nov 20, 2019Peer-reviewedSystems Biology