Systems BiologyJournal of Biological ChemistryPeer-reviewed
Evolved resistance to GAPDH inhibition results in loss of the Warburg Effect but retains a different state of glycolysis
Maria V. Liberti, Annamarie E. Allen, Vijyendra Ramesh…·Jason W. Locasale
This study evolves resistance to GAPDH inhibition and shows that cells lose the Warburg Effect but maintain a distinct glycolytic state with different metabolic dependencies.
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