Zufeng Guo

This paper identifies rapaglutin E as a specific inhibitor of GLUT1 and explores its binding mechanism compared to rapaglutin A.

This paper identifies rapaprotin as a 26S proteasome assembly inhibitor that is activated by PREP to induce apoptosis and synergizes with proteasome inhibitors in cancer cells.

This study evolves resistance to GAPDH inhibition and shows that cells lose the Warburg Effect but maintain a distinct glycolytic state with different metabolic dependencies.