Molecular BiologybioRxivPreprint
Age-associated repression of HNF4α is a driver and potential therapeutic target in liver metabolic dysfunction
Jessica Proulx, Kathryn A Lande, Xue Lei…·Peter D Adams
This study identifies age-associated repression of HNF4α as a driver of liver metabolic dysfunction and shows that restoring HNF4α can reverse some age-related liver defects.