MADDD-seq, a novel massively parallel sequencing tool for simultaneous detection of DNA damage and mutations
Marc Vermulst, Samantha Paskvan, Claire S Chung, Kathryn Franke, Nigel J. Clegg, Sam Minot, Jennifer J. Madeoy, Annalyssa Long, Jean-François Goût, Jason H. Bielas
MADDD-seq detects DNA damage and mutations simultaneously in yeast using a modified double barcoding sequencing approach, revealing repair kinetics and mutagenesis over 24 hours.
Nucleic Acids Research · Jul 17, 2024Peer-reviewedGenetics