Author

Annalyssa Long

Fred Hutch Cancer Center

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cancer Biology· 1 Genetics· 1 Genomics· 1 Immunology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Organism:human· 2 Approach:statistical model· 2 Assay:whole-genome sequencing· 2 Approach:benchmark study· 1 Research Focus:benchmarking· 1

Frequent Co-Authors

Anna ElziD· 3 shared Evan William NewelliD· 2 shared Sam MinotiD· 2 shared Amelia R. WilhelmiD· 1 shared Andrew J. SnyderiD· 1 shared Anshu BandhlishiD· 1 shared Azi Hadadianpour· 1 shared Brittany R. BarberiD· 1 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersCancer Biology

Anna ElzORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Dysregulation of epithelial differentiation architecture underlies field cancerization in head and neck cancer

Claire Mills, Yin Huang, Chan Mi Lee, Connor Finkbeiner, Rachel K. Lex, Dominik J. Otto, Ruijin Yang, Hoku West‐Foyle, Daniel Jones, Annalyssa Long, Sam Minot, Emma Nguyen, Pushpa Itagi, Samantha Schuster, Anna Elz, , Slobodan Beronja

This study identifies molecular and architectural changes in normal-adjacent field tissue in HNSCC that disrupt epithelial differentiation and may promote cancer development.

bioRxiv · Oct 14, 2026 · PreprintCancer Biology

Modulating AP-1 enables CAR-T cells to establish an intratumoral PD-1+Tcf1+ stem-like reservoir and overcomes resistance to PD-1 axis blockade

Andrew J. Snyder, Sarah M. Garrison, Mitchell G. Kluesner, W. Sam Nutt, Carolyn Shasha, T. T. Giang Ho, Sydney A. Marsh, Miles Hamilton Linde, Feinan Wu, Lauren K. Meyer, Amelia R. Wilhelm, Sergio Ortiz‐Espinosa, Victor Zepeda, Emma Bingham, Haleema S. Malik, , Shivani Srivastava

This study shows that overexpressing c-Jun in CAR-T cells enhances their ability to maintain PD-1+Tcf1+ stem-like cells in tumors and improves response to PD-L1 blockade.

Science Immunology · Mar 6, 2026Peer-reviewedImmunology

Evaluating the practical aspects and performance of commercial single-cell RNA sequencing technologies

Anna Elz, Derrik Gratz, Annalyssa Long, David Sowerby, Azi Hadadianpour, Evan William Newell

This study compares commercial single-cell RNA sequencing platforms based on performance metrics and practical considerations.

NAR Genomics and Bioinformatics · Dec 11, 2025Peer-reviewedGenomics

MADDD-seq, a novel massively parallel sequencing tool for simultaneous detection of DNA damage and mutations

Marc Vermulst, Samantha Paskvan, Claire S Chung, Kathryn Franke, Nigel J. Clegg, Sam Minot, Jennifer J. Madeoy, Annalyssa Long, Jean-François Goût, Jason H. Bielas

MADDD-seq detects DNA damage and mutations simultaneously in yeast using a modified double barcoding sequencing approach, revealing repair kinetics and mutagenesis over 24 hours.

Nucleic Acids Research · Jul 17, 2024Peer-reviewedGenetics