Author

Samantha Paskvan

Fred Hutch Cancer Center

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genetics· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:yeast· 2 Research Focus:variant calling· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Aaron W. MilleriD· 1 shared Annalyssa Long· 1 shared Bonita J. BreweriD· 1 shared Christopher R. L. LargeiD· 1 shared Claire S ChungiD· 1 shared Claudia Y. EspinozaiD· 1 shared Cole Van BruinisseiD· 1 shared Gina M. AlvinoiD· 1 shared

Activity by Year

2024-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperGenomics

Aaron W. MillerORCID

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2 papers

Recent·Most cited

MADDD-seq, a novel massively parallel sequencing tool for simultaneous detection of DNA damage and mutations

Marc Vermulst, Samantha Paskvan, Claire S Chung, Kathryn Franke, Nigel J. Clegg, Sam Minot, Jennifer J. Madeoy, Annalyssa Long, Jean-François Goût, Jason H. Bielas

MADDD-seq detects DNA damage and mutations simultaneously in yeast using a modified double barcoding sequencing approach, revealing repair kinetics and mutagenesis over 24 hours.

Nucleic Acids Research · Jul 17, 2024Peer-reviewedGenetics

Template switching between the leading and lagging strands at replication forks generates inverted copy number variants through hairpin-capped extrachromosomal DNA

Rebecca Martin, Claudia Y. Espinoza, Christopher R. L. Large, Joshua Rosswork, Cole Van Bruinisse, Aaron W. Miller, Joseph C. Sanchez, Madison A. Miller, Samantha Paskvan, Gina M. Alvino, Maitreya J. Dunham, M. K. Raghuraman, Bonita J. Brewer

The paper identifies a replication error mechanism called ODIRA that generates inverted copy number variants through template switching at replication forks, using yeast as a model system.

PLoS Genetics · Jan 4, 2024Peer-reviewedGenomics