Author

Katia P. Karalis

Regeneron (United States)

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1 Genetic & Genomic Medicine· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Organism:human· 2 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:mouse· 1 Approach:statistical model· 1

Frequent Co-Authors

Kristen Howell· 2 shared Shek Man ChimiD· 2 shared Adam E. LockeiD· 1 shared Alan R. ShuldineriD· 1 shared Alexander H. LiiD· 1 shared Alexandros G. KokkosisiD· 1 shared Anthony MarckettaiD· 1 shared Aris N. EconomidesiD· 1 shared

Activity by Year

2024-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

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2 shared papersGenetic & Genomic Medicine

Kristen Howell

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Genetic inactivation of zinc transporter SLC39A5 improves liver function and hyperglycemia in obesogenic settings

Shek Man Chim, Kristen Howell, John Dronzek, Weizhen Wu, Cristopher V. Van Hout, Manuel A. R. Ferreira, Bin Ye, Alexander H. Li, Susannah D. Brydges, Arunachalam Vinayagam, Anthony Marcketta, Adam E. Locke, Jonas Bovijn, Niek Verweij, Tanima De, , Harikiran Nistala

The paper identifies SLC39A5 as a gene whose loss-of-function variants are associated with reduced type II diabetes risk and improved liver function in metabolic disorders.

eLife · Dec 13, 2024Peer-reviewedGenetic & Genomic Medicine

A Human Brain-Chip for modelling brain pathologies and screening of BBB crossing therapeutic strategies

Shek Man Chim, Kristen Howell, Alexandros G. Kokkosis, Brian Zambrowicz, Katia P. Karalis, Elias Pavlopoulos

The paper develops a human Brain-Chip model to study brain pathologies and test BBB-crossing therapies, showing in vitro/in vivo correlation for drug screening.

Pharmaceutics · Oct 10, 2024Peer-reviewedBioengineering