Author

Kayla Frank

Scripps Research Institute

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:development & morphogenesis· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Silke PaustiD· 2 shared Angel Gandarilla· 1 shared Naushad KhaniD· 1 shared Shawn A. AbeynaikeiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

4 top collaborators · 4 mutual co-author links

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2 shared papersImmunology

Silke PaustORCID

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2 papers

Recent·Most cited

CXCR6⁺ natural killer cell immunotherapy preserves CD4⁺ T helper cells in humanized mice

Naushad Khan, Kayla Frank, Silke Paust

This study shows that CXCR6⁺ NK cells reduce HIV replication and preserve CD4⁺ T cells in humanized mice, suggesting their potential as an immunotherapy strategy.

Frontiers in Immunology · Aug 10, 2026Peer-reviewedImmunology

TRAIL-mediated PMN-MDSC depletion prevents CD4+ T cell loss in HIV-infectedhumanized mice

Shawn A. Abeynaike, Kayla Frank, Angel Gandarilla, Silke Paust

This study shows that TRAIL-R2 agonist treatment reduces MDSCs in HIV-infected mice, prevents CD4+ T cell loss, and enhances immune function.

bioRxiv · Jan 22, 2025 · PreprintImmunology