Developmental BiologyNaturePeer-reviewed
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An epigenetic barrier sets the timing of human neuronal maturation
Gabriele Ciceri, Arianna Baggiolini, Hyunwoo Cho…·Lorenz Studer
Chromatin regulators including EZH2, EHMT1/2, and DOT1L establish an epigenetic barrier in human neural progenitors that poises maturation genes and sets the protracted pace of cortical neuron maturation.