Author

Keir Maclean

University of Oxford

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 1 Approach:experimental assay· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

Anna Gesine HuhniD· 1 shared Audrey GérardiD· 1 shared Jagdish N. MahaleiD· 1 shared Lion F. K. UhliD· 1 shared Mikhail A. KutuzoviD· 1 shared Omer DushekiD· 1 shared P. Anton van der MerweiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

7 top collaborators · 21 mutual co-author links

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1 shared paperImmunology

Anna Gesine HuhnORCID

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1 paper

Recent·Most cited

The 3D affinities of the OT-I TCR to foreign and self-antigens predict their 2D affinities and reveal imperfect antigen discrimination

Anna Gesine Huhn, Mikhail A. Kutuzov, Keir Maclean, Lion F. K. Uhl, Jagdish N. Mahale, Audrey Gérard, P. Anton van der Merwe, Omer Dushek

This paper measures 3D affinities of the OT-I TCR to 19 pMHC complexes and finds they strongly correlate with 2D membrane affinities, revealing imperfect antigen discrimination.

bioRxiv · Jan 12, 2025 · PreprintImmunology