Author

Lion F. K. Uhl

University of OxfordORCID 0000-0003-1729-9857Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 1 Approach:experimental assay· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

Anna Gesine HuhniD· 1 shared Audrey GérardiD· 1 shared Jagdish N. MahaleiD· 1 shared Keir Maclean· 1 shared Mikhail A. KutuzoviD· 1 shared Omer DushekiD· 1 shared P. Anton van der MerweiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

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7 top collaborators · 21 mutual co-author links

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1 shared paperImmunology

Anna Gesine HuhnORCID

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1 paper

Recent·Most cited

ImmunologybioRxivPreprintJan 12, 2025

The 3D affinities of the OT-I TCR to foreign and self-antigens predict their 2D affinities and reveal imperfect antigen discrimination

Anna Gesine Huhn, Mikhail A. Kutuzov, Keir Maclean…·Omer Dushek

This paper measures 3D affinities of the OT-I TCR to 19 pMHC complexes and finds they strongly correlate with 2D membrane affinities, revealing imperfect antigen discrimination.

2 citations

mouseproteomics

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