Multiple ecological and evolutionary mechanisms drive treatment-induced antibiotic resistance
Matthew James Shepherd, Niamh E. Harrington, Anastasia Kottara, Claudia Igler, Kenny Cagney, Taoran Fu, Elizabeth M. Grimsey, Joanne L. Fothergill, Dylan Z. Childs, Steve Paterson, Michael A. Brockhurst
This study analyzes antibiotic resistance emergence in Pseudomonas aeruginosa during treatment, finding that pre-existing resistance and ecological dynamics drive resistance development.
bioRxiv · Feb 19, 2026 · PreprintEvolutionary Biology