A tetracycline antibiotic minocycline prevents early aging phenotypes in mice heterozygous for RP58
Tomoko Tanaka, Shinobu Hirai, Hiroyuki Manabe, Kentaro Endo, Yasumasa Nishito, Hiroko Shimbo, Hikari Yoshitane, Haruo Okado
This study shows that minocycline prevents early aging phenotypes in Rp58 hetero-KO mice by mitigating DNA damage and cognitive decline.
bioRxiv · Sep 18, 2021 · PreprintNeuroscience