GeneticsGenome biologyPeer-reviewed
SETDB1 prevents TET2-dependent activation of IAP retroelements in naïve embryonic stem cells
Özgen Deniz, Lorenzo de la Rica, Kevin C. L. Cheng…·Miguel Ramos Branco
This study shows that SETDB1 prevents TET2 from demethylating H4R3 in IAP retroelements in naive ESCs, maintaining their silencing.
54 citations