Author

Khoi Pham Munchic

Broad Institute

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Systems Biology· 1

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Research Focus:benchmarking· 1 Assay:proteomics· 1 Approach:statistical model· 1

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Alessandro LussanaiD· 1 shared Aurélien J. F. DugourdiD· 1 shared Bing ZhangiD· 1 shared D.R. ManiiD· 1 shared Eric J. JaehnigiD· 1 shared Evangelia PetsalakiiD· 1 shared Jared Lee JohnsoniD· 1 shared Jonathan Thomas LeiiD· 1 shared

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1 paper

Recent·Most cited

Comprehensive evaluation of phosphoproteomic-based kinase activity inference

Sophia Müller‐Dott, Eric J. Jaehnig, Khoi Pham Munchic, Wen Jiang, Tomer M. Yaron, Sara R. Savage, Martín Garrido‐Rodríguez, Jared Lee Johnson, Alessandro Lussana, Evangelia Petsalaki, Jonathan Thomas Lei, Aurélien J. F. Dugourd, Karsten Krug, Lewis C. Cantley, D.R. Mani, , Julio Sáez-Rodríguez

This paper evaluates kinase activity inference methods using phosphoproteomics data and benchmarking approaches, finding that curated kinase-substrate libraries significantly impact results.

Nature Communications · May 22, 2025Peer-reviewedSystems Biology