Author

Wen Jiang

Baylor College of Medicine

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Biology Disciplines

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Systems Biology· 2

Signature Assays, Organisms & Methods

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Approach:statistical model· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:gene regulatory network inference· 1 Assay:proteomics· 1

Frequent Co-Authors

Alessandro LussanaiD· 1 shared Aurélien J. F. DugourdiD· 1 shared Bing ZhangiD· 1 shared D.R. ManiiD· 1 shared Degeng WangiD· 1 shared Denis FéliersiD· 1 shared Eric J. JaehnigiD· 1 shared Evangelia PetsalakiiD· 1 shared

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2022-2025 · peak 1/yr

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10 top collaborators · 24 mutual co-author links

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1 shared paperSystems Biology

Alessandro LussanaORCID

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2 papers

Recent·Most cited

Comprehensive evaluation of phosphoproteomic-based kinase activity inference

Sophia Müller‐Dott, Eric J. Jaehnig, Khoi Pham Munchic, Wen Jiang, Tomer M. Yaron, Sara R. Savage, Martín Garrido‐Rodríguez, Jared Lee Johnson, Alessandro Lussana, Evangelia Petsalaki, Jonathan Thomas Lei, Aurélien J. F. Dugourd, Karsten Krug, Lewis C. Cantley, D.R. Mani, , Julio Sáez-Rodríguez

This paper evaluates kinase activity inference methods using phosphoproteomics data and benchmarking approaches, finding that curated kinase-substrate libraries significantly impact results.

Nature Communications · May 22, 2025Peer-reviewedSystems Biology

Bridging Transcriptome Regulation and Cellular Operational Efficiency with the Locality and Caching System Optimization Principles

Wen Jiang, Denis Féliers, Wenjin Jim Zheng, Fangyuan Zhang, Degeng Wang

The paper applies computer science principles of locality and caching to explain transcriptome regulation and cellular efficiency in gene expression.

bioRxiv · Jan 11, 2022 · PreprintSystems Biology