Chemogenetic Inhibition of Infralimbic Prefrontal Cortex GABA-ergic Parvalbuminpositive Interneurons Attenuates Chronic Stress Adaptions in Male Mice
Nawshaba Nawreen, Evelin M. Cotella, Rachel L. Morano, Parinaz Mahbod, Khushali S. Dalal, Maureen E. Fitzgerald, Susan E. Martelle, Benjamin A. Packard, Ana Cecilia González Franco, Rachel D. Moloney, James P. Herman
This study inhibits prefrontal cortex parvalbumin interneurons in mice using DREADDs and shows that it reduces chronic stress-related behaviors and physiological changes.
eNeuro · Sep 1, 2020Peer-reviewedNeuroscience