Evelin M. Cotella

Adolescent Stress Exposure: Behavioral Consequences and Molecular Mechanisms in Corticolimbic Networks

This study investigates the long-term behavioral and molecular effects of adolescent chronic variable stress in rats, revealing sex- and region-specific changes in corticolimbic circuits.

Genetic activation of ERK2 recapitulates core neurodevelopmental features of Rasopathy syndromes in mice

This study shows that genetic activation of ERK2 in mice models key neurodevelopmental features of Rasopathy syndromes, including cognitive impairments and facial dysmorphology.

Sex-Specific Regulation of Behavioral Responses to Single Prolonged Stress: Role of PACAP

This study investigates sex-specific effects of PACAP in a PTSD model, finding differential behavioral outcomes in male and female rats following stress.

Ventral striatal dopamine encodes unique properties of visual stimuli in mice

This study shows that dopamine release in the lateral shell of the ventral striatum encodes visual stimulus properties like luminance changes rather than threat level in mice.

Adolescent Stress Confers Resilience to Traumatic Stress Later in Life: Role of the Prefrontal Cortex

This study shows that adolescent stress can reduce the negative effects of traumatic stress in adulthood, with sex-specific changes in brain regions involved in fear responses.

Chemogenetic Inhibition of Infralimbic Prefrontal Cortex GABA-ergic Parvalbuminpositive Interneurons Attenuates Chronic Stress Adaptions in Male Mice

This study inhibits prefrontal cortex parvalbumin interneurons in mice using DREADDs and shows that it reduces chronic stress-related behaviors and physiological changes.

Selective modulation of the glucocorticoid receptor with CORT108297 during chronic adolescent stress evokes sex specific effects in adulthood.

This study examines how adolescent chronic stress affects behavior and physiology differently in male and female rats, with GR signaling playing a role in some outcomes.