Rachel L. Morano

Adolescent Stress Exposure: Behavioral Consequences and Molecular Mechanisms in Corticolimbic Networks

This study investigates the long-term behavioral and molecular effects of adolescent chronic variable stress in rats, revealing sex- and region-specific changes in corticolimbic circuits.

Infralimbic cortical glutamate output is necessary for the neural and behavioral consequences of chronic stress

This study shows that reducing glutamate output in the infralimbic cortex of rats alters neural activity and behavior after chronic stress, highlighting its role in stress-related disorders.

Chemogenetic Inhibition of Infralimbic Prefrontal Cortex GABA-ergic Parvalbuminpositive Interneurons Attenuates Chronic Stress Adaptions in Male Mice

This study inhibits prefrontal cortex parvalbumin interneurons in mice using DREADDs and shows that it reduces chronic stress-related behaviors and physiological changes.

Prefrontal Cortex Regulates Chronic Stress-Induced Cardiovascular Susceptibility

This study shows that reducing glutamate release from infralimbic cortex neurons increases cardiovascular reactivity and vascular dysfunction under chronic stress.

Selective modulation of the glucocorticoid receptor with CORT108297 during chronic adolescent stress evokes sex specific effects in adulthood.

This study examines how adolescent chronic stress affects behavior and physiology differently in male and female rats, with GR signaling playing a role in some outcomes.

Use of CRISPR/Cas9 Gene Targeting to Conditionally Delete Glucocorticoid Receptors in Rat Brain

This study uses CRISPR/Cas9 to create a conditional GR knockout in rats, showing sex-specific behavioral effects of GR deletion in the prelimbic cortex.