Author

Kiera O’Keefe

St. Jude Children's Research Hospital

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Genomics· 1

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Approach:experimental assay· 1 Organism:human· 1 Research Focus:variant calling· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Akshay SharmaiD· 1 shared Alicia Powers· 1 shared Cícera Regina LazzarottoiD· 1 shared Erin DempseyiD· 1 shared Frank Fazio· 1 shared GaHyun LeeiD· 1 shared Garret ManqueniD· 1 shared Jingjing ZhangiD· 1 shared

Activity by Year

2024-2024 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperGenomics

Akshay SharmaORCID

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1 paper

Recent·Most cited

GenomicsMolecular TherapyPeer-reviewedJul 30, 2024

Development and IND-enabling studies of a novel Cas9 genome-edited autologous CD34+ cell therapy to induce fetal hemoglobin for sickle cell disease

Varun Katta, Kiera O’Keefe, Yichao Li…·Shengdar Q. Tsai

This study develops a genome-edited autologous CD34+ cell therapy to induce fetal hemoglobin for sickle cell disease, showing efficient editing, therapeutic HbF levels, and no off-target effects.

18 citations

humanwhole-genome sequencing

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