A CD57+ cytotoxic CD8 T cell subset associated with fibrotic lung disease in systemic sclerosis
Takanori Sasaki, Ye Cao, Kathryne E. Marks, Kazuhiko Higashioka, Mehreen Elahee, Richard I. Ainsworth, Kim Taylor, Nunzio Bottini, Paul J. Wolters, Mari Kamiya, Edy Yong Kim, Francesco Boin, Deepak A. Rao
The paper identifies a CD57+ cytotoxic CD8 T cell subset expanded in SSc-ILD patients and links it to lung injury through CD155-CD226 interactions.
bioRxiv · Jan 27, 2025 · PreprintImmunology