Kathryne E. Marks

This study identifies pre-treatment naive CD4+ T cell abundance as a predictor of severe irAEs in patients receiving anti-PD-1/CTLA4 checkpoint inhibitor therapy for melanoma.

This study uses single-cell RNA sequencing to identify CD4+ T cell phenotypes in psoriasis patients associated with response to IL-23 blockade.

This study identifies granzyme K as a driver of a novel complement activation pathway independent of classical, lectin, or alternative pathways.

The paper identifies a CD57+ cytotoxic CD8 T cell subset expanded in SSc-ILD patients and links it to lung injury through CD155-CD226 interactions.

This study shows clonal overlap between Tph and Tfh cells in SLE patients and mice, suggesting shared developmental pathways and potential implications for immunosuppressive treatment.

The paper maps cell-type-specific eQTLs for HLA genes across multiple tissues and identifies dynamic regulation of HLA-DQ genes in immune cells.