Author

Mehreen Elahee

Brigham and Women's Hospital

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:bulk RNA-seq· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Deepak A. RaoiD· 3 shared Kathryne E. MarksiD· 2 shared Alice HorisbergeriD· 1 shared Andreea M. BujoriD· 1 shared Anne R. BassiD· 1 shared Bernhard NieswandtiD· 1 shared Caroline Fromson· 1 shared Denisa D. WagneriD· 1 shared

Activity by Year

2025-2025 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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3 shared papersImmunology

Deepak A. RaoORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Pre-treatment naive T cells are associated with severe irAE following PD-1/CTLA4 checkpoint blockade for melanoma

Kathryne E. Marks, Alice Horisberger, Mehreen Elahee, Ifeoluwakiisi Adejoorin, Nilasha Ghosh, Michael Andrew Postow, Laura T. Donlin, Anne R. Bass, Deepak A. Rao

This study identifies pre-treatment naive CD4+ T cell abundance as a predictor of severe irAEs in patients receiving anti-PD-1/CTLA4 checkpoint inhibitor therapy for melanoma.

JCI Insight · Nov 25, 2025Peer-reviewedImmunology

A CD57+ cytotoxic CD8 T cell subset associated with fibrotic lung disease in systemic sclerosis

Takanori Sasaki, Ye Cao, Kathryne E. Marks, Kazuhiko Higashioka, Mehreen Elahee, Richard I. Ainsworth, Kim Taylor, Nunzio Bottini, Paul J. Wolters, Mari Kamiya, Edy Yong Kim, Francesco Boin, Deepak A. Rao

The paper identifies a CD57+ cytotoxic CD8 T cell subset expanded in SSc-ILD patients and links it to lung injury through CD155-CD226 interactions.

bioRxiv · Jan 27, 2025 · PreprintImmunology

A GPVI-platelet-neutrophil-NET axis drives systemic sclerosis

Roxane Darbousset, Gonzalo Villanueva-Martín, Julia Kuehn, Stefano Navarro, Spoorthi Balu, Dhruv Miglani, Eilish Dillon, Caroline Fromson, Leetah Senkpeil, Mehreen Elahee, Pierre‐André Jarrot, Sydney B. Montesi, Deepak A. Rao, Jerry L. Ware, Denisa D. Wagner, , Peter Andrija Nigrovic

This study identifies a GPVI-platelet-neutrophil-NET axis that drives systemic sclerosis fibrosis and presents it as a therapeutic target.

bioRxiv · Jan 21, 2025 · PreprintImmunology