Age-Related Decline in Blood-Brain Barrier Function is More Pronounced in Males than Females in Parietal and Temporal Regions
Xingfeng Shao, Qinyang Shou, Kimberly Felix, Brandon Ojogho, Xuejuan Jiang, Brian T. Gold, Megan M. Herting, Eric Luria Goldwaser, Peter V Kochunov, Elliot L. Hong, Ioannis Pappas, Meredith N. Braskie, Hosung Kim, Steven Cen, Kay Jann, Danny J.J. Wang
The paper investigates age and sex differences in BBB function using MRI in 186 participants, finding more pronounced decline in males starting in the early 60s, particularly in parietal and temporal regions.
bioRxiv · Jan 12, 2024Neuroscience