Xingfeng Shao

The paper maps human hippocampal perfusion and microvascular pulsatility across age using MRI and integrates these with histological and transcriptomic data, revealing distinct spatial organization and age-related differences.

The paper introduces CCSI, a metric linking cortical blood flow and cellular architecture, showing its correlation with metabolic and structural features across brain regions.

This study uses DP-pCASL to measure BBB water exchange rates before and after FUS-mediated BBB opening in non-human primates, finding localized decreases and global increases in Kw.

The paper introduces a T2*-informed multivariate sample entropy method for fMRI data to better measure brain complexity and shows it detects significant group differences in older vs. younger adults.

The paper uses factor analysis on multimodal biomarkers to identify latent constructs of brain health, finding five distinct constructs associated with age and cognitive function.

This study examines relationships between MRI-based measures of neurovascular integrity and fluid transport in older adults, finding age-related changes and stable inter-relationships among these metrics.

The paper investigates age and sex differences in BBB function using MRI in 186 participants, finding more pronounced decline in males starting in the early 60s, particularly in parietal and temporal regions.

This paper introduces a 3D zoomed arterial spin labeling technique at 7T to quantitatively measure laminar cerebral blood flow in human brain regions during rest and task activation.