Electrical Stimulation Rejuvenates Tunicates: Altered Stem Cell and Immune Activity
Jos Domen, Yotam Voskoboynik, Tom Levy, Erica M. Domen, Katherine J. Ishizuka, Karla J. Palmeri, Chiara Anselmi, Thomas Rolander, Norma F Neff, Angela M. Detweiler, Irving L. Weissman, Kimberly Lynn Gandy, Debashis Sahoo, Ayelet Voskoboynik
The paper shows that pulsatile electrical current improves survival, regeneration, and reproduction in Botryllus schlosseri by altering stem cell and immune activity through transcriptomic changes.
bioRxiv · May 17, 2025 · PreprintDevelopmental Biology