BiophysicsbioRxivPreprint
Single molecule studies of the bacterial curli protein CsgA reveal a structurally dynamic monomeric structure
Daniel A. N. Foster, Kirill Kudriavtsev, Calum Ryan Byrne…·Derek R. Dee
This study uses single-molecule force spectroscopy to reveal that CsgA exists in metastable folded states and disordered states, which are aggregation-prone and previously uncharacterized at the ensemble level.
DOI 10.1101/2025.09.08.674806