Author

Kirill Makedonski

Hebrew University of Jerusalem

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Developmental Biology· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Organism:mouse· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1 Assay:DNA methylation· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Shulamit Sebban· 2 shared Yosef BuganimiD· 2 shared Ahmed Radwan· 1 shared Amnon KoreniD· 1 shared Areej KhatibiD· 1 shared Aurélie ErnstiD· 1 shared Britny Blumenfeld· 1 shared Hagit Masika· 1 shared

Activity by Year

2018-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersDevelopmental Biology

Shulamit Sebban

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2 papers

Recent·Most cited

Comparative Parallel Multi-Omics Analysis During the Induction of Pluripotent and Trophectoderm States

Mohammad Jaber, Ahmed Radwan, Netanel Loyfer, Mufeed Abdeen, Shulamit Sebban, Areej Khatib, Hazar Yassen, Thorsten Kolb, Marc Zapatka, Kirill Makedonski, Aurélie Ernst, Tommy Kaplan, Yosef Buganim

This study compares the reprogramming dynamics of pluripotent and trophoblast stem cell states using multi-omics analysis, revealing distinct trajectories and reprogramming markers.

Nature Communications · Jun 17, 2022Peer-reviewedDevelopmental Biology

Germline DNA replication timing shapes mammalian genome composition

Yishai Yehuda, Britny Blumenfeld, Nina Mayorek, Kirill Makedonski, Oriya Vardi, Leonor Cohen‐Daniel, Yousef Mansour, Shulamit Sebban, Hagit Masika, Marganit Farago, Michael F. Berger, Shai Carmi, Yosef Buganim, Amnon Koren, Itamar Simon

The paper measures DNA replication timing in mouse germline cells and shows it strongly correlates with mutation rates, recombination hotspots, and genomic features compared to somatic tissues.

Nucleic Acids Research · Jun 26, 2018Peer-reviewedGenomics