Yosef Buganim

This study compares the reprogramming dynamics of pluripotent and trophoblast stem cell states using multi-omics analysis, revealing distinct trajectories and reprogramming markers.

This study shows Esrrb promotes XEN differentiation in G2/M phase ESCs and is required for XEN differentiation potential, while its absence leads to loss of differentiation capacity.

This paper introduces a method to generate localized DNA double-strand breaks in cell populations using UV-irradiation with photomasks, enabling the study of genome rearrangements and DNA damage response.

The paper measures DNA replication timing in mouse germline cells and shows it strongly correlates with mutation rates, recombination hotspots, and genomic features compared to somatic tissues.