A systematic cross-modal approach identifies astrocytic VCAM1 as a regulator of hippocampal synapse development
Cydric Geyskens, Efstathia Kotoula, Kjen Bogaert, Elke Leysen, Joris Vandenbempt, Francisco Pestana, L. J. LeFever, Pedro Magalhães, Dan Dascenco, Joris de Wit
The paper identifies VCAM1 as an astrocytic regulator of hippocampal synapse development through cross-modal analysis combining single-cell spatial transcriptomics and protein-level profiling.
bioRxiv · Mar 18, 2026 · PreprintNeuroscience